Life extension
Life extension, broadly defined, is the cause that works to further advances in biomedical treatments, specifically those related to aging. Below, we outline the importance, tractability, and neglectedness of life extension, in line with our general questions for causes.
Anti-aging may be more relevant, as it incorporates the decrease in healthspan seen in age that’s relevant for reasons beyond life/longevity extension (e.g. fluid intelligence decline with age)
Importance
Do we want to lose someone like Elon Musk or Edward O. Wilson?
For raw estimates of impact, see the importance of life extension.
Objections and counter-objections
Main article: Arguments against life extension
Given that a variety of criticisms have been put forth against life extension, it is important consider whether life extension is even a cause with positive outcomes. A variety of counter-objections, also known as Keyhole solutions, are also explored; this is especially important because preventing life extension may be impossible. These issues are explored in the following:
- Life extension and overpopulation considers the argument that if people stop dying, the world will become overpopulated, leading to some sort of disaster.
- Life extension and stagnation considers the argument that if old people don’t die, they will stay in power, be a majority, stop human evolution, etc., so that society will become stagnant.
- Distribution of life extension treatments considers the argument that when life extension treatments become available, they will only be affordable for the rich, leading to e.g. ethical problems.
Tractability
Main article: Tractability of life extension
Neglectedness
Main article: Neglectedness of life extension
Potential actions
- Ways You Can Contribute to Gerontology
- The Importance of Activism
- Worthy Causes suggests donating and learning more.
Intersections
- Life extension and artificial intelligence
- Life extension and people’s mentality
- Life extension and romance
Donors
Sean Parker donated $600 million to launch the Parker Foundation, which focuses on three areas: Life Sciences, Global Public Health, and Civic Engagement and donated $250 million to create the Parker Institute for Cancer Immunotherapy.
The Open Philanthropy Project also made some donations in this space.
Prizes
Organizations
Investors
Discussion group
- Effective Altruism & Life Extension (Facebook group)
Popular opinion
Aubrey de Grey says that very few people think aging is feasible and undesirable, and so someone that think it’s undesirable and unfeasible updates on the feasibility of it, they would also be likely to update on the desirability of it (source: 5:45 Longevity Myth Busting - Aubrey de Grey).
Timeline
External links
- Effective Altruism & Biological Aging: Resources
- Anti-aging research fits under the broader category of biomedical research. See for instance this GiveWell post.
- Wikipedia’s page on it
- Aubrey de Grey on Quora, and SENS
- Evan Gaensbauer’s comment
- Fight Aging!, and other websites like it
- http://senescence.info/, which has Links on Aging
- http://www.vincegiuliano.name/Antiagingfirewalls.htm and http://www.anti-agingfirewalls.com/ (though these seem more about the science rather than the Importance, tractability, and neglectedness of fighting aging)
- For SENS in particular, there is “Tentative Thoughts on the Cost Effectiveness of the SENS Foundation” and a 2012 conversation between Holden Karnofsky and Aubrey de Grey.
- Bryan Caplan’s posts on life extension:
- Also discussed to some extent in “Intellectual Hipsters and Meta-Contrarianism”.
- Why people want to die
- A History of Life-Extensionism in the Twentieth Century might be interesting to look through
- Also read more about Michael Rae
- “Is peer review slowing down science and technology?”
- https://www.facebook.com/groups/effective.altruists/permalink/1001166419939715/
- The Rejuvenation Roadmap
- How to help work on longevity by Laura Deming
- 2021 Longevity Challenges
- AgingBiotech.info